Cell Maps for Artificial Intelligence (CM4AI) http://CM4AI.org will deliver machine-readable hierarchical maps of cell architecture as AI-ready data, together with quarterly data releases of map-input data streams. CM4AI cell maps are produced from multimodal interrogation of chromatin modifiers, metabolic enzymes, and other proteins involved in cancer, neuropsychiatric, and cardiac disorders in disease-relevant cell lines under treated and untreated conditions, utilizing state-of-the-art mass spectrometry-based proteomics, spatial proteomics / cell imaging, and genetic perturbations via CRISPR/Cas9. CM4AI is a collaboration of UCSD, UCSF, Stanford, UVA, Yale, UT Austin, UA Birmingham, Simon Fraser University, and the Hastings Center, as part of the NIH Bridge2AI program.
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Cell Maps for Artificial Intelligence - June 2025 Data Release (Beta)
Dec 22, 2025
Clark T; Parker J; Al Manir S; Axelsson U; Ballllosero Navarro F; Chinn B; Churas CP; Dailamy A; Doctor Y; Fall J; Forget A; Gao J; Hansen JN; Hu M; Johannesson A; Khaliq H; Lee YH; Lenkiewicz J; Levinson MA; Marquez C; Metallo C; Muralidharan M; Nourreddine S; Niestroy J; Obernier K; Pan E; Polacco B; Pratt D; Qian G; Schaffer L; Sigaeva A; Thaker S; Zhang Y; Bélisle-Pipon JC; Brandt C; Chen JY; Ding Y; Fodeh S; Krogan N; Lundberg E; Mali P; Payne-Foster P; Ratcliffe S; Ravitsky V; Sali A; Schulz W; Ideker T, 2025, "Cell Maps for Artificial Intelligence - June 2025 Data Release (Beta)", https://doi.org/10.18130/V3/F3TD5R, University of Virginia Dataverse, V3
Description This dataset is a revision of the June 2025 Data Release of Cell Maps for Artificial Intelligence (CM4AI; CM4AI.org), the Functional Genomics Grand Challenge in the NIH Bridge2AI program. This revision includes adding RGB immunofluorescent images, corrections to ro-crate metadata, and changes to naming conventions. This Beta release inc...
Cell Maps for Artificial Intelligence - October 2025 Data Release (Beta)
Dec 22, 2025
Clark, T; Parker, J; Al Manir, S; Axelsson, U; Ballllosero Navarro, F; Chinn, B; Churas, CP; Dailamy, A; Doctor, Y; Fall, J; Forget, A; Gao, J; Hansen, JN; Hu, M; Johannesson, A; Khaliq, H; Lee, YH; Lenkiewicz, J; Levinson, MA; Marquez, C; Metallo, C; Muralidharan, M; Nourreddine, S; Niestroy, J; Obernier, K; Pan, E; Polacco, B; Pratt, D; Qian, G; Schaffer, L; Sigaeva, A; Thaker, S; Zhang, Y; Bélisle-Pipon, JC; Brandt, C; Chen, JY; Ding, Y; Fodeh, S; Krogan, N; Lundberg, E; Mali, P; Payne-Foster, P; Ratcliffe, S; Ravitsky, V; Sali, A; Schulz, W; Ideker, T, 2025, "Cell Maps for Artificial Intelligence - October 2025 Data Release (Beta)", https://doi.org/10.18130/V3/K7TGEM, University of Virginia Dataverse, V2
Description This dataset is the October 2025 Data Release of Cell Maps for Artificial Intelligence (CM4AI; CM4AI.org), the Functional Genomics Grand Challenge in the NIH Bridge2AI program. CM4AI is generating multi-modal data including protein-protein interaction (PPI), spatial localization, and genetic perturbation data in MDA-MB-468 breast cancer...
Cell Maps for Artificial Intelligence - March 2025 Data Release (Beta)
Mar 3, 2025
Clark T; Parker J; Al Manir S; Axelsson U; Ballllosero Navarro F; Chinn B; Churas CP; Dailamy A; Doctor Y; Fall J; Forget A; Gao J; Hansen JN; Hu M; Johannesson A; Khaliq H; Lee YH; Lenkiewicz J; Levinson MA; Marquez C; Metallo C; Muralidharan M; Nourreddine S; Niestroy J; Obernier K; Pan E; Polacco B; Pratt D; Qian G; Schaffer L; Sigaeva A; Thaker S; Zhang Y; Bélisle-Pipon JC; Brandt C; Chen JY; Ding Y; Fodeh S; Krogan N; Lundberg E; Mali P; Payne-Foster P; Ratcliffe S; Ravitsky V; Sali A; Schulz W; Ideker T, 2025, "Cell Maps for Artificial Intelligence - March 2025 Data Release (Beta)", https://doi.org/10.18130/V3/B35XWX, University of Virginia Dataverse, V1
This dataset is the March 2025 Data Release of Cell Maps for Artificial Intelligence (CM4AI; CM4AI.org), the Functional Genomics Grand Challenge in the NIH Bridge2AI program. This Beta release includes perturb-seq data in undifferentiated KOLF2.1J iPSCs; SEC-MS data in undifferentiated KOLF2.1J iPSCs and iPSC-derived NPCs, neurons, and cardiomyocyt...
Cell Maps for Artificial Intelligence - Data Release
May 11, 2024
Clark, Timothy; Schaffer, Leah; Obernier, K; Al Manir, Sadnan; Churas, Christopher; Dailamy, A; Doctor, Y; Forget, A; Hansen, JN; Hu, M; Lenkiewicz, J; Levinson, MA; Marquez, C; Mohan, J; Nourreddine, S; Niestroy, J; Pratt, D; Qian, G; Thaker, S; Belisle-Pipon, J-C; Brandt, C; Chen, J; Ding, Y; Fodeh, S; Krogan, N; Lundberg, E; Mali, P; Payne-Foster, P; Ratcliffe, S; Ravitsky, V; Sali, A; Schulz, W; Ideker, T, 2024, "Cell Maps for Artificial Intelligence - Data Release", https://doi.org/10.18130/V3/DXWOS5, University of Virginia Dataverse, V1
This collection is the 0.5 alpha data release of the the Cell Maps for Artificial Intelligence (CM4AI) Functional Genomics Data Generation Project, a component of the U.S. National Institute of Health’s (NIH) Bridge2AI program. CM4AI’s objective is to deliver machine-readable hierarchical maps of cell architecture as AI-Ready data produced from mul...
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